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We and other workers found that DNA is synthesized in vitro in neuronal nuclei by DNA polymerase X3,1)-3) which is thought to participate in repair of chromatin DNA.In addition, we demonstrated in vitro joining of single-stranded DNA at the nicks of neuronal chromatin DNA and suggested that DNA ligase responsible for this joining might be present in neuronal nuclei.4)In the present
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Inoue et al. (1976) studied this question.
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