Why the study?
Management of patients with transposition of the great arteries and intact ventricular septum can be challenging beyond the newborn period, prompting an evaluation of an alternative strategy for left ventricular training.
Does bidirectional cavopulmonary anastomosis with pulmonary artery banding provide effective left ventricular training in patients with transposition of the great arteries and intact ventricular septum?
Observational (n=6)
Yes
Does bidirectional cavopulmonary anastomosis with pulmonary artery banding provide effective left ventricular training in patients with transposition of the great arteries and intact ventricular septum?
Answers are grounded in this paper and cite their sources.
May support bidirectional cavopulmonary anastomosis with pulmonary artery banding for left ventricular training in transposition of the great arteries with intact ventricular septum; leaves open prospective validation.
OBJECTIVE: Management of the patients with transposition of the great arteries and intact ventricular septum may be challenging beyond the newborn period. Herein, we would like to present our alternative strategy for training the left ventricle in these patients. METHODS: Six patients with transposition of the great arteries and intact ventricular septum were evaluated in our clinic. Two of them were palliated with Glenn procedure and pulmonary banding as a definitive treatment strategy at other centers. Four patients were operated on and a bidirectional cavopulmonary anastomosis in combination with pulmonary artery banding was performed (stage-1: palliation and ventricular training) in our center. In four out of these six patients, arterial switch operation was performed with takedown and direct re-anastomosis of the superior vena cava to right atrium after an interstage period of 21-30 months (stage-2: anatomical repair). RESULTS: in patients undergoing the anatomical repair. All of the patients were uneventfully discharged following the second stage. The mean follow-up period was 20 months (9-32 months) following stage 2. All of the patients are doing well with trivial neoaortic regurgitation and normal biventricular function. CONCLUSIONS: Bidirectional cavopulmonary anastomosis with pulmonary artery banding may be a promising left ventricle training approach in ventriculoarterial discordance when compared to the traditional pulmonary artery banding with concomitant systemic-to-pulmonary artery shunt procedures which still carry a significant interstage morbidity and mortality.
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Bilal et al. (2019) conducted an observational in Transposition of the great arteries and intact ventricular septum (n=6). Bidirectional cavopulmonary anastomosis and pulmonary artery banding was evaluated on Clinical outcomes (survival, neoaortic regurgitation, biventricular function).
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