Evidence for lack of antigenic competition among various combinations of Vibrio anguillarum, Yersinia ruckeri, Aeromonas salmonicida and Renibacterium salmoninarum bacterins when administered to salmonid fishes

Bacterins of Vibrio anguillarum, Yersinia ruckeri, Aeromonas Salmonicida, and Renibacterum salmoninarum were administered alone and in combination to salmonid fishes and the level of protective immunity compared. With each pathogen, the protection obtained with monovalent with A. salmonicida bacterin alone conferred some protection against challenges with Type II V. anguillarum and Y. ruckeri. Also, the combination of A. salmonicida and R. salmoninarum bacterins appeared to potentiate the protection conferred against A. salmonicida. The potential of multivalent vaccines for protecting fish from several diseases appears to be real.