Key result
Early myogenesis intrinsically determines muscle specialization with fiber heterogeneity driven by hormone-modulated cell generations.
Population
developing muscle models (chicken, rat)
Design
Review
Authors
Loading...
Early fiber-type programming may constrain training responses in athletes; leaves open hormonal modulation as a research target.
This review highlights that muscle fiber specialization is determined early in development and modulated post-partum by hormonal factors.
Kelly et al. (1986) conducted a review in Neuromuscular specialization during development. Muscle specialization during development is intrinsically determined early in myogenesis, with fiber heterogeneity resulting from distinct primary and secondary cell generations modulated by hormones.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: