Key result
In a middle-aged female patient with cardiac myxosarcoma, the tumor recurred locally and metastasized post-surgery, and did not respond to subsequent chemotherapy and radiotherapy.
Why the study?
Myxosarcoma accounts for a very small proportion of primary cardiac malignancies and lacks specificity in clinical manifestations or imaging features.
Case Report (n=1)
Cardiac myxosarcoma is a rare, aggressive primary malignant tumor that can mimic myxoma on imaging and may be resistant to chemotherapy and radiotherapy.
Answers are grounded in this paper and cite their sources.
Echocardiography may misclassify cardiac myxosarcoma as myxoma; leaves open whether multimodality imaging aids preoperative differentiation.
Myxosarcoma only accounts for a very small proportion of primary malignant tumors of the heart. The disease has no specificity in clinical manifestations or features on medical images. In this case study, we report about a middle-aged female patient afflicted with cardiac myxosarcoma. The initial transthoracic echocardiography of the patient revealed a cardiac myxoma. However, the postoperative histopathology confirmed the presence of a malignant cardiac myxosarcoma. Post-surgery follow-up imaging examinations revealed local recurrence in the left atrium as well as soft-tissue and bone metastases. The recurrent tumor and metastases were subsequently treated with chemotherapy and radiotherapy. However, the tumor did not respond to treatment and the disease progressed.
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Zheng et al. (2022) conducted a case report in Cardiac myxosarcoma (n=1). Surgery, chemotherapy, and radiotherapy was evaluated on Clinical course and tumor response. In a middle-aged female patient with cardiac myxosarcoma, the tumor recurred locally and metastasized post-surgery, and did not respond to subsequent chemotherapy and radiotherapy.
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