Key result
Takotsubo cardiomyopathy features temporary LV dysfunction triggered by severe stress and mediated by catecholamines.
Why the study?
This article was written to briefly discuss the relationship between emotional stressors and cardiac dysfunction in Takotsubo cardiomyopathy.
This review highlights the essential role of the sympathetic nervous system and catecholamines in mediating emotional stress-induced cardiac dysfunction in Takotsubo cardiomyopathy.
Supports sympathetic-targeted therapies in Takotsubo; leaves open clinical efficacy pending prospective trials.
Takotsubo cardiomyopathy (TTC) or Takotsubo syndrome is a syndrome indicated by the presence of temporary left ventricle (LV) regional systolic dysfunction which mimics the symptoms of myocardial infarction. TTS patients have been reported to experience severe and sudden emotional or physical distress and the previous diagnosis of psychiatric disorders may be reported among some of the patients indicating the relationship between an emotional stressor and cardiac dysfunction. The sympathetic nervous system and catecholamines play an essential role to mediate the effect of emotional stressors on the heart. This article briefly discusses the relationship between the emotional stressor and cardiac dysfunction in TTC.
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Kristian S. Hartanto (2021) conducted a review in Takotsubo Cardiomyopathy. Emotional stress was evaluated. Takotsubo cardiomyopathy is a temporary left ventricular dysfunction often triggered by severe emotional or physical stress, mediated by sympathetic nervous system activation and catecholamines.
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