Key result
Aortic valve repair and reconstruction, guided by advanced multimodality imaging, can preserve the native valve and delay the need for replacement in adolescents and young adults.
Why the study?
Adolescents and young adults with congenital aortic valve disease often require multiple interventions during their lifetime, necessitating evolving lifetime management strategies to preserve the native aortic valve.
Highlights the importance of tailored surgical approaches and multimodality imaging to preserve the native aortic valve in adolescents and young adults with congenital aortic valve disease.
May support imaging-guided repair to delay replacement in select young patients; leaves open need for prospective trials on durability.
In this invited expert review, we focus on evolving lifetime management strategies for adolescents and young adults with congenital aortic valve disease, acknowledging that these patients often require multiple interventions during their lifetime. Our goal is to preserve the native aortic valve when feasible. Leveraging advanced multimodality imaging, a detailed assessment of the aortic valve and root complex can be obtained, and a surgically approach tailored to an individual patient's anatomy and pathology can be used. In turn, aortic valve repair and reconstruction can be offered to a greater number of patients, either as a definitive strategy or as a component of a staged strategy to delay the need for aortic valve replacement until later in life when more options are available.
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Frankel et al. (2024) conducted a review in Congenital aortic valve disease. Aortic valve repair and reconstruction was evaluated. Aortic valve repair and reconstruction, guided by advanced multimodality imaging, can preserve the native valve and delay the need for replacement in adolescents and young adults.
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