Key result
Admission HbA1c level was significantly higher in nondiabetic unstable angina patients with an ejection fraction ≤50% compared to those with >50% (P=0.01).
Why the study?
Is admission HbA1c level associated with reduced ejection fraction in nondiabetic patients with unstable angina?
Cross-Sectional (n=231)
Is admission HbA1c level associated with reduced ejection fraction in nondiabetic patients with unstable angina?
Admission HbA1c may serve as a useful prognostic marker for reduced ejection fraction in nondiabetic patients presenting with unstable angina.
May support HbA1c as marker for reduced EF; hypothesis-generating in nondiabetic unstable angina, needs prospective validation.
Introduction: There have been incompatible evidences about the prognostic value of HbA1c on the adverse outcomes in acute coronary syndrome. Also, these data are so limited in nondiabetic patients with unstable angina.Methods: In this cross-sectional study, HbA1c level of 231 nondiabetic patients admitted with unstable angina, was measured using high performance liquid affinity chromatography (HPLC) at admission. Then transthoracic echocardiography (TTE) was performed for evaluation of ejection fraction (EF) using Simpson method.Results: Our data revealed that HbA1c was significantly higher in patients with EF≤ 50% in comparison with EF>50% group (P value=0.01).Conclusions: HbA1c may be a helpful prognostic marker in nondiabetic patients admitted in emergency department with diagnosis of unstable angina.
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Parsa et al. (2016) conducted a cross-sectional in Unstable angina (n=231). Admission HbA1c level was evaluated on Ejection fraction ≤ 50% (p=0.01). Admission HbA1c level was significantly higher in nondiabetic unstable angina patients with an ejection fraction ≤50% compared to those with >50% (P=0.01).
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