Key result
Elevated HbA1c predicts ~41% higher in-hospital mortality in STEMI patients undergoing primary PCI.
Why the study?
Does elevated HbA1c predict worse in-hospital outcomes in patients with STEMI undergoing primary PCI?
Population
374 consecutive patients with ST-segment elevation myocardial infarction undergoing primary percutaneous…
Comparison
Elevated hemoglobin A1c levels measured within… vs Normal hemoglobin A1c levels.
Design
Cohort
Follow-up
In-hospital
Authors
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May aid risk stratification in STEMI; leaves open whether targeting HbA1c improves outcomes.
Cohort (n=374)
Does elevated HbA1c predict worse in-hospital outcomes in patients with STEMI undergoing primary PCI?
Odds Ratio: 1.412 (95% CI 1.031–1.935)
Absolute Event Rate: 11% vs 0.9%
p-value: p=0.03
Elevated HbA1c is an independent predictor of in-hospital mortality and major adverse cardiac events in STEMI patients undergoing primary PCI, and can help identify previously undiagnosed diabetes.
Çiçek et al. (2011) conducted a cohort in ST-segment elevation myocardial infarction (STEMI) (n=374). Elevated Hemoglobin A1c (HbA1c ≥6.5%) vs. HbA1c ≤5.6% and 5.7-6.4% was evaluated on In-hospital mortality (OR 1.412, 95% CI 1.031-1.935, p=0.03). Elevated HbA1c was an independent predictor of in-hospital mortality in patients with STEMI undergoing primary PCI (OR 1.412; 95% CI 1.031-1.935; P=0.03).
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