Key result
Donepezil was successfully used to treat cognitive deficits associated with maintenance electroconvulsive therapy in a single case report.
Why the study?
Does donepezil improve cognition in patients with cognitive impairment caused by maintenance electroconvulsive therapy?
Case Report (n=1)
Does donepezil improve cognition in patients with cognitive impairment caused by maintenance electroconvulsive therapy?
Donepezil may be a useful treatment for cognitive deficits associated with maintenance ECT, though further studies are needed.
Cognitive deficits are commonly associated with maintenance electroconvulsive therapy (ECT). Treatment of these cognitive deficits is important but difficult. Cholinergic pathways are involved in these side effects, and donepezil, a cholinesterase inhibitor, may be useful for improvement of cognition. In this case report, we describe for the first time successful use of donepezil in treating cognitive deficits associated with maintenance ECT. The role of cholinesterase inhibitors in the treatment of cognitive deficits caused by ECT needs further studies.
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Rao et al. (2009) conducted a case report in Cognitive impairment caused by maintenance electroconvulsive therapy (n=1). Donepezil was evaluated on Improvement of cognitive deficits. Donepezil was successfully used to treat cognitive deficits associated with maintenance electroconvulsive therapy in a single case report.
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