The 5‐hydroxymethyl and the 5‐formyl‐1‐cyclopropyl‐6‐fluoro‐7‐piperazinyl‐1,4‐dihydro‐4‐oxo‐1,8‐naphthyridine‐3‐carboxylic acids have been prepared via a 5‐trimethylsilyl group and were tested in vitro as potential antibacterials.
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Remuzon et al. (1992) studied this question.
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