Key result
Single-dose garlic oil reduces adrenaline-induced platelet aggregation by ~12% without affecting collagen or ADP.
Why the study?
Does a single large dose of garlic oil reduce platelet aggregation in healthy volunteers?
RCT (n=14)
Double-blind
Randomized crossover
Does a single large dose of garlic oil reduce platelet aggregation in healthy volunteers?
Effect estimate: 12% reduction
p-value: p=<0.05
A single large dose of garlic oil does not meaningfully reduce platelet aggregation and should not be relied upon for clinical antiplatelet effects.
No takes yet. Share an insight, caveat, or question.
Single large-dose garlic oil lacks meaningful antiplatelet activity; challenges traditional claims and should not guide clinical use or further acute trials.
Wojcikowski et al. (2007) conducted an RCT in Healthy (n=14). Solvent-extracted garlic oil vs. Placebo was evaluated on Platelet aggregation induced ex vivo by adrenaline, collagen or ADP (12% reduction, p=<0.05). A single large dose of garlic oil had little effect on platelet aggregation in healthy volunteers, reducing adrenaline-induced aggregation by 12% (P<0.05) with no effect on collagen or ADP.
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