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Early descriptions of the Frank-Starling mechanism were published by Elias Cyon in 1866 and Joseph Coats in 1869, who demonstrated the effect of diastolic filling on cardiac ejection volume.
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Does not alter current hemodynamics practice; extends the documented origins of the Frank-Starling mechanism to 1866.
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Heinz‐Gerd Zimmer (2002) studied this question. Early descriptions of the Frank-Starling mechanism were published by Elias Cyon in 1866 and Joseph Coats in 1869, who demonstrated the effect of diastolic filling on cardiac ejection volume.
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