March 5, 2010European Journal of Cardio-Thoracic Surgery
Trans-apical aortic valve implantation: univariate and multivariate analyses of the early results from the SOURCE registry☆☆☆
Key result
Trans-apical TAVI is linked to ~10% 30-day mortality in high-risk patients.
- n=575
Population
575 patients at high risk for aortic valve replacement undergoing trans-apical trans-catheter aortic valve…
Design
Cohort
Follow-up
30-day
Authors
Discussion
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Member takes
Implication
Signals caution for trans-apical TAVI in high-risk patients; leaves open optimal access strategies pending randomized evidence.
Study Design
Type
Observational (n=575)
Multicenter
Yes
Structured PICO
P
Population
575 high-risk patients undergoing trans-apical trans-catheter aortic valve implantation at European centers, evaluated for 30-day postoperative mortality.
E
Exposure
Trans-apical trans-catheter aortic valve implantation (using Edwards SAPIEN bioprosthesis)
O
Outcome
30-day mortalityhard clinical
Trans-apical TAVI in high-risk patients demonstrates a 92.7% procedural success rate and 10.3% 30-day mortality, with very high logistic EuroSCOREs predicting inferior survival.
Cite This Study
Wendler et al. (2010) conducted an observational in High risk for aortic valve replacement (n=575). Trans-apical trans-catheter aortic valve implantation was evaluated on 30-day mortality. Trans-apical trans-catheter aortic valve implantation in high-risk patients resulted in a 30-day mortality of 10.3%.