Key result
SPECT and EEG in infantile convulsions reveal increased ictal and decreased interictal left frontal perfusion.
Case Report (n=1)
Epileptic foci in benign familial infantile convulsions show similar perfusion characteristics on SPECT as symptomatic partial epilepsy.
SPECT perfusion patterns in benign familial infantile convulsions may mimic symptomatic epilepsy; leaves open whether imaging reliably differentiates benign from symptomatic infantile seizures.
Ictal and interictal single photon emission computed tomography (SPECT) and ictal electroencephalography (EEG) were studied in a 3-month-old girl with benign familial infantile convulsions (BFIC) to reveal the epileptic focus. There was bilateral diffuse propagation from a left frontal lobe focus on the ictal EEG. Perfusion in the left frontal region was increased on ictal SPECT and decreased on interictal SPECT. Epileptic foci of BFIC showed the same characteristics as foci of symptomatic partial epilepsy.
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Nagase et al. (2002) conducted a case report in Benign familial infantile convulsions (n=1). Ictal and interictal SPECT and ictal EEG was evaluated on Epileptic focus localization and perfusion characteristics. Ictal and interictal SPECT and ictal EEG in a 3-month-old girl with benign familial infantile convulsions revealed increased left frontal perfusion during seizures and decreased perfusion interictally.
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