Key result
Steatosis is linked to ~21% higher odds of multi-site atherosclerosis and improves Framingham risk prediction.
Why the study?
Is steatosis associated with specific and multiple-site atherosclerosis and higher 10-year Framingham Risk Score in patients with cardiovascular risk factors?
Population
2,554 patients with one or more cardiovascular risk factors, free of cardiovascular events and other chronic…
Comparison
Presence of steatosis detected by the fatty… vs Absence of steatosis (FLI < 60)
Design
Cross-sectional
Authors
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Steatosis links to carotid/coronary but not femoral atherosclerosis and refines FRS prediction; leaves open whether it improves event risk stratification beyond CVRF.
Cross-Sectional (n=2,554)
Is steatosis associated with specific and multiple-site atherosclerosis and higher 10-year Framingham Risk Score in patients with cardiovascular risk factors?
Odds Ratio: 1.21 (95% CI 1.01–1.45)
p-value: p=0.035
Steatosis is independently associated with carotid and coronary atherosclerosis, and its inclusion improves cardiovascular risk prediction beyond classical risk factors.
Pais et al. (2018) conducted a cross-sectional in Cardiovascular risk factors without prior events (n=2,554). Steatosis vs. No steatosis was evaluated on At least 2-site atherosclerosis (OR 1.21, 95% CI 1.01-1.45, p=0.035). Steatosis was independently associated with at least 2-site atherosclerosis (OR 1.21; 95% CI 1.01-1.45; P=0.035) and improved the prediction of a 10-year Framingham Risk Score ≥10%.
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