What is the clinical evidence from this study?

Study design: Cohort. Population: Elective cardiac surgery (n=3150). Intervention: Sedentary lifestyle vs. Active lifestyle. Primary outcome: Hospital mortality (OR 1.2, 95% CI 0.4-3.5, p=0.617).

July 2, 2013Netherlands Heart JournalOpen Access

Is a sedentary lifestyle an independent predictor for hospital and early mortality after elective cardiac surgery?

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Key result

Sedentary lifestyle does not independently predict hospital or early mortality after elective cardiac surgery.

OR 1.2
95% CI 0.4-3.5
P=0.617
n=3,150

Why the study?

Does a sedentary lifestyle independently predict hospital and early mortality in patients undergoing elective cardiac surgery?

Population

3,150 patients undergoing elective cardiac surgery between January 2007 and June 2012, mean age 69.7 ± 10.1…

Comparison

Sedentary lifestyle as classified by the… vs Active lifestyle as classified by the same…

Design

Cohort

Follow-up

Hospital stay and early postoperative period

Authors

LNL. NoyezRadboud University Nijmegen IBI. BiemansRadboud University Nijmegen MVMichel VerkroostInterventional / Structural Cardiology

Discussion

Member takes

Implication

Does not support sedentary lifestyle as independent mortality predictor after elective cardiac surgery; leaves open whether activity interventions improve outcomes in prospective studies.

Study Design

Type

Cohort (n=3,150)

Multicenter

Structured PICO

Does a sedentary lifestyle independently predict hospital and early mortality in patients undergoing elective cardiac surgery?

Population

3,150 adult patients undergoing elective cardiac surgery who completed a preoperative physical activity questionnaire, followed for up to 30 days postoperatively.

Exposure

Sedentary lifestyle (n=1335) as classified by the preoperative Corpus Christi Heart Project questionnaire

Comparator

Active lifestyle (n=1815) as classified by the same questionnaire

Outcome

Hospital mortality and early mortalityhard clinical

Main Result

Odds Ratio: 1.2 (95% CI 0.4–3.5)

Absolute Event Rate: 1.1% vs 0.4%

p-value: p=0.617

Although sedentary patients have higher crude hospital and early mortality after elective cardiac surgery, a sedentary lifestyle is not an independent predictor of these outcomes.

Limitations

The physical activity questionnaire used may not be specific enough to identify a sedentary lifestyle compared to objective tests like gait speed.
The inclusion of both high and low-risk patients may have diluted the effect, as mortality was very low overall.
Low prevalence of the primary outcome parameters (hospital and early mortality).
Follow-up was limited to 30 days, ignoring events occurring months after surgery.

Cite This Study

Noyez et al. (2013) conducted a cohort in Elective cardiac surgery (n=3,150). Sedentary lifestyle vs. Active lifestyle was evaluated on Hospital mortality (OR 1.2, 95% CI 0.4-3.5, p=0.617). Although associated with higher unadjusted mortality, a sedentary lifestyle was not an independent predictor for hospital mortality (OR 1.2) or early mortality (OR 1.1) after elective cardiac surgery.

synapsesocial.com/papers/6aa4551c0ff716c22769d5de https://doi.org/10.1007/s12471-013-0444-5

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Implication

Does not support sedentary lifestyle as independent mortality predictor after elective cardiac surgery; leaves open whether activity interventions improve outcomes in prospective studies.

Is a sedentary lifestyle an independent predictor for hospital and early mortality after elective cardiac surgery?

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Is a sedentary lifestyle an independent predictor for hospital and early mortality after elective cardiac surgery?

Discussion

Member takes

Implication

Study Design

Structured PICO

Main Result

Limitations

Cite This Study

Also Consider

Also Consider