Key result
Following the reinforced Ross operation, 24% of patients required subsequent aortic reintervention over a mean follow-up of 6.1 years, with a median time to reintervention of 41.8 months.
Why the study?
The Ross operation remains controversial due to late autograft dilation and progressive neo-aortic insufficiency, prompting the development of the reinforced Ross procedure.
Cohort (n=25)
No
The reinforced Ross operation demonstrates excellent mid-term survival and stable aortic root dimensions, though early experience is associated with a learning curve leading to a 24% reintervention rate.
Reinforced Ross yields acceptable short-term hemodynamics in pediatrics; leaves open durability and generalizability pending larger prospective trials.
BACKGROUND: The Ross operation for aortic valve replacement continues to be a controversial option because of concerns related to late autograft dilation and progressive neo-aortic insufficiency. In 2005, the reinforced Ross procedure was described at our institution to address this problem. We aim to analyze the short and mid-term outcomes following this procedure. METHODS: This is a retrospective study of patients who underwent the reinforced Ross operation between 2004 and 2019. A comprehensive chart review was performed. Echocardiograms were independently reviewed by an adult congenital cardiologist. The time to reintervention was evaluated with a Kaplan-Meier curve. Analysis was conducted in JMP 15.1 (SAS Inc., Cary, NC). RESULTS: Twenty-five patients underwent the reinforced Ross operation. Twenty-three patients (92%) had bicuspid aortic valve and the most common indication for surgery was a combination of aortic insufficiency and stenosis (n = 18, 72%). The mean follow-up was 6.1 ± 5.0 years. All patients were alive at the time of follow-up. Six patients (24%), from early in our experience, required subsequent aortic reintervention. Median time to reintervention was 41.8 months (0-81.5 months). Sixteen (64%) patients had less than moderate aortic insufficiency at last follow-up. Additionally, average aortic root measurements remained unchanged. CONCLUSIONS: The reinforced Ross technique was initially proposed as a way to mitigate aortic root dilation seen in the traditional Ross procedure. Our experience suggests an associated learning curve with the majority of aortic reinterventions occurring within the first few years following surgery. Continued follow-up is warranted to assess its long-term durability and functionality.
No takes yet. Share an insight, caveat, or question.
Leeds et al. (2021) conducted a cohort in Aortic valve disease (n=25). Reinforced Ross operation was evaluated on Aortic reintervention. Following the reinforced Ross operation, 24% of patients required subsequent aortic reintervention over a mean follow-up of 6.1 years, with a median time to reintervention of 41.8 months.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: