Key result
Dural puncture epidural cuts time to first painless contraction by ~47% vs standard epidural.
Why the study?
Epidural analgesia can be associated with slow onset and inadequate block, prompting evaluation of dural puncture epidural to balance analgesia quality and side effects.
Does Dural puncture epidural (DPE) improve the quality and effectiveness of labor analgesia compared to classical epidural analgesia in women in labor?
RCT (n=80)
No
Does Dural puncture epidural (DPE) improve the quality and effectiveness of labor analgesia compared to classical epidural analgesia in women in labor?
Absolute Event Rate: 11.4% vs 21.5%
p-value: p=<0.05
Dural puncture epidural provides faster onset and better quality of labor analgesia compared to classical epidural analgesia without increasing maternal or fetal complications.
DPE may improve labor analgesia quality; leaves open its advantages over standard epidural in larger randomized trials.
Epidural analgesia (EA), most commonly used for labor analgesia, is an effective and relatively safe technique, but may be associated with slow onset, inadequate block. The use of Dural puncture epidural (DPE) is designed to find a balance between improving the quality of analgesia and reducing the frequency of side effects. Purpose - to compare two methods of labor analgesia. Materials and methods. All women (n=80) were divided into two groups: the Group I (n=40) used DPE, the Group II (n=40) used EA. In both groups, the same technique of epidural puncture and catheterization was used, in the Group I additionally puncture of the dura mater. Analgesia was evaluated using the visual analog pain rating scale (VAS). The quality and effectiveness of analgesia, the hemodynamics of the woman were evaluated. Complications and unwanted effects were recorded. Fetal condition: cardiotocography (CTG), umbilical cord blood lactate, pH. A statistical analysis of the obtained data was carried out. Results. The first contraction (VAS1) in the Group I were fixed on 11.43.3 min, and in the Group II on 21.57.2 min (p0.05). Monolateral block in the Group I - 4 (10%) versus 10 (25%) (p0.05). Contractions (VAS 1) after 30 min in the Group II - 7 (17.5%) versus the absence of such in the Group I. Stroke volume in the Group I decreased by 2.1% versus 1.5% in the Group II. The data for hypotension and occurrence of complications, CTG, cord blood lactate, and pH were not different by group. Conclusions. The use of the DPE technique against EA gives better results in terms of the quality and effectiveness of analgesia. The mother’s hemodynamics remained stable when using DPE. The DPE technique does not increase the frequency of complications compared to EA. There was no difference between the groups when assessing the state of the fetus according to CTG data, pH indicators and umbilical cord blood lactate. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author.
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Ye.M. Sulimenko (2023) conducted an RCT in Labor pain (n=80). Dural puncture epidural (DPE) vs. Standard epidural analgesia (EA) was evaluated on Time to first painless contraction (VAS < 1) in minutes (p=<0.05). Dural puncture epidural significantly reduced the time to the first painless contraction to 11.4 minutes compared to 21.5 minutes with standard epidural analgesia.
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