Key result
Study comparing atenolol and metoprolol for MI risk in elective surgery reports no quantitative results.
Why the study?
Does atenolol provide equivalent reductions in risk of myocardial infarction compared to metoprolol in older patients undergoing elective surgery?
Cohort
Does atenolol provide equivalent reductions in risk of myocardial infarction compared to metoprolol in older patients undergoing elective surgery?
No results reported to inform beta-blocker selection; leaves open whether atenolol and metoprolol differ for perioperative MI risk in older elective surgery patients.
The objective of the study was to test whether atenolol (a long acting beta blocker) and metoprolol (a short acting beta blocker) are associated with equivalent reductions in risk for older patients undergoing elective surgery. Myocardial infarction is a common complication after elective surgery and blockers are believed to reduce that risk. Sudden withdrawal of beta blockers may result in tachycardia, hypertension and cardiac ischaemia. The loss of the blockade around the time of surgery may predispose the patient to a myocardial infarction.
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Ruth Sander (2006) conducted a cohort in Elective surgery. Atenolol vs. Metoprolol was evaluated on Risk reduction (myocardial infarction). The abstract outlines a study to compare atenolol and metoprolol in older patients undergoing elective surgery but reports no quantitative results.
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