Key result
PERT implementation is linked to an ~83% faster CTEPH diagnosis after acute PE.
Why the study?
Diagnostic delay remains a major barrier to timely CTEPH treatment, and evidence on the impact of pulmonary embolism response teams on CTEPH diagnostic timing is scant.
Does multidisciplinary PERT implementation reduce time to CTEPH diagnosis in patients with acute pulmonary embolism?
Cohort (n=29)
No
Does multidisciplinary PERT implementation reduce time to CTEPH diagnosis in patients with acute pulmonary embolism?
Absolute Event Rate: 43% vs 256%
p-value: p=0.0369
Implementation of a multidisciplinary pulmonary embolism response team (PERT) in a general hospital setting significantly reduced the time to diagnosis of chronic thromboembolic pulmonary hypertension (CTEPH).
PERT may accelerate CTEPH diagnosis after PE; leaves open effects on outcomes and generalizability.
Chronic thromboembolic pulmonary hypertension (CTEPH) is a potentially curable form of pulmonary hypertension, yet diagnostic delay remains a major barrier to timely treatment. Pulmonary embolism response teams (PERT) have emerged as a strategy to optimize follow-up after acute pulmonary embolism (APE), but local evidence on their impact on CTEPH diagnostic timing is scant. We conducted a single-center, retrospective cohort study comparing patients diagnosed with CTEPH before and after PERT implementation in a general hospital in Argentina. Among 29 patients, those diagnosed after PERT implementation had a significantly shorter time from APE to CTEPH diagnosis (median 43 vs. 256 weeks, p=0.0369) and a non-significant trend toward lower-risk profiles at diagnosis. These findings support the role of structured multidisciplinary follow-up in accelerating CTEPH recognition outside specialized referral centers.
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Souto et al. (2026) conducted a cohort in Chronic thromboembolic pulmonary hypertension (CTEPH) (n=29). Pulmonary embolism response team (PERT) implementation vs. Pre-PERT implementation period was evaluated on Time from acute pulmonary embolism to CTEPH diagnosis (weeks) (p=0.0369). Implementation of a pulmonary embolism response team significantly reduced the median time from acute pulmonary embolism to CTEPH diagnosis from 256 weeks to 43 weeks (p=0.0369).
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