What question did this study set out to answer?

To assess the impact of portal vein arterialization on hepatic hemodynamics and long-term clinical outcomes in liver transplant recipients.

July 1, 2001American Journal of TransplantationOpen Access

Outcome and Hepatic Hemodynamics in Liver Transplant Patients with Portal Vein Arterialization

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Authors

RCR. CharcoUniversitat Autònoma de Barcelona CMCarlos MargaritHospital General Universitario de Alicante Doctor Balmis JLJuan Carlos López-TalaveraOncoGenex Pharmaceuticals (United States)

Discussion

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Implication

Case series reveals stable hepatic hemodynamics and acceptable graft survival in liver transplant recipients undergoing portal vein arterialization, suggesting a viable salvage option.

Key Points

To assess the impact of portal vein arterialization on hepatic hemodynamics and long-term clinical outcomes in liver transplant recipients.
Evaluated three patients undergoing liver transplantation with portal vein arterialization: two with splanchnic venous thrombosis receiving orthotopic grafts and one with fulminant hepatic failure receiving an auxiliary heterotopic graft.
Monitored post-transplant liver function, wedged and free hepatic venous pressures, and graft histology via biopsy.
Immediate postoperative graft function was excellent across all three patients, with two surviving long-term and one dying at four months post-transplant.
Hemodynamic evaluation demonstrated a normal pressure gradient between wedged and free hepatic venous pressures in all recipients.
One patient developed prehepatic portal hypertension and variceal bleeding secondary to an arterioportal fistula at 14 months, which resolved following hepatic artery embolization.

Cite This Study

Charco et al. (2001) studied this question.

synapsesocial.com/papers/6aa4a1a02fdbcb5be994df39 https://doi.org/10.1034/j.1600-6143.2001.10208.x

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Implication

Case series reveals stable hepatic hemodynamics and acceptable graft survival in liver transplant recipients undergoing portal vein arterialization, suggesting a viable salvage option.

Outcome and Hepatic Hemodynamics in Liver Transplant Patients with Portal Vein Arterialization

Discussion

Member takes

Implication

Key Points

Cite This Study

Outcome and Hepatic Hemodynamics in Liver Transplant Patients with Portal Vein Arterialization

Discussion

Member takes

Implication

Key Points

Cite This Study

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