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July 19, 2018The Open Orthopaedics JournalOpen Access

Is it Possible to Recover Cardiac Functions After Total Knee Arthroplasty?

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Key result

TKA followed by brisk walking is linked to an ~8% improvement in LV diastolic function.

  • P<0.001
  • n=109

Why the study?

Does Total Knee Arthroplasty improve cardiac functions and functional capacity in patients with knee osteoarthritis?

Population

109 patients with knee osteoarthritis who underwent Total Knee Arthroplasty (TKA)

Design

Cohort

Follow-up

one year

Authors

AAAydın ArslanBÇBilal ÇuğlanBÖBülent Özkurt

Discussion

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Overview

May improve LV diastolic function after TKA in knee OA; hypothesis-generating and should not yet change practice.

Study Design

Type

Observational (n=109)

Structured PICO

Does Total Knee Arthroplasty improve cardiac functions and functional capacity in patients with knee osteoarthritis?

P
Population
109 patients (mean age 66.8 years, 88% female) with knee osteoarthritis who underwent total knee arthroplasty and a prescribed walking program, followed for one year.
I
Intervention
Total Knee Arthroplasty (TKA)
O
Outcome
Cardiac functions (Doppler echocardiography E/A and Em/Am ratios) and functional capacity (WOMAC, SF-36, step count, 6MWT, FTSST) at one yearsurrogate

Main Result

Absolute Event Rate: 0.77% vs 0.71%

p-value: p=<0.001

Total knee arthroplasty in osteoarthritis patients is associated with increased physical activity and improved echocardiographic markers of diastolic cardiac function at one year.

Limitations

  • Use of pedometers instead of more accurate accelerometers to measure physical activity.
  • Exclusion of patients with serious mobility problems limits generalizability and comparability with other studies.

Cite This Study

Arslan et al. (2018) conducted an observational in Knee osteoarthritis (n=109). Total knee arthroplasty and brisk walking program vs. Preoperative baseline was evaluated on Left ventricular diastolic function (E/A ratio) (p=<0.001). Total knee arthroplasty followed by a brisk walking program significantly improved left ventricular diastolic function, increasing the mean E/A ratio from 0.71 to 0.77 at one year.

synapsesocial.com/papers/6aa4aae2997531f8901427adhttps://doi.org/10.2174/1874325001812010261
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cardiovascular responses to exercise. Effects of aging and exercise training in healthy men.1994 · 453 citations
  2. 2Relative Intensity of Physical Activity and Risk of Coronary Heart Disease2003 · 346 citations
  3. 3Physical Activity, All-Cause Mortality, and Longevity of College Alumni1986 · 2,763 citations
  4. 4Effect of Aging and Physical Activity on Left Ventricular Compliance2004 · 539 citations