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Dynamic gating behaviour of ionic nanochannel is precisely manipulated by cyclic 3′,5′-adenosine monophosphate (cAMP) by taking advantage of reversible conformational transition of the smart polymer chains in response to cAMP specific adsorption, which provides a new idea for developing smart nanochannels regulated by crucial signal-biomolecules.
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Chen et al. (2019) studied this question.
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