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February 1, 1998The Annals of Thoracic Surgery219 citationsOpen Access

Left Ventricular Volume Predicts Postoperative Course in Patients With Ischemic Cardiomyopathy

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AYAtsushi YamaguchiTITakashi InoHAHideo Adachi

Key Result

A preoperative LVESVI >100 mL/m2 was an independent predictor of death and associated with a higher rate of postoperative congestive heart failure compared to LVESVI <100 mL/m2 (62.5% vs 8.7%).

Study Design

Type

Cohort (n=41)

Structured PICO

Does preoperative LVESVI predict death and postoperative congestive heart failure in patients with ischemic cardiomyopathy and EF < 0.30?

P
Population
41 patients with ischemic cardiomyopathy and a preoperative ejection fraction of less than 0.30.
E
Exposure
Preoperative left ventricular end-systolic volume index (LVESVI) > 100 mL/m2
C
Comparator
Preoperative LVESVI < 100 mL/m2
O
Outcome
Death and development of postoperative congestive heart failurehard clinical

Preoperative LVESVI > 100 mL/m2 is a strong independent predictor of mortality and postoperative congestive heart failure in patients with ischemic cardiomyopathy and severe left ventricular dysfunction.

Main Result

Absolute Event Rate: 62.5% vs 8.7%

Abstract

BACKGROUND: The left ventricular end-systolic volume index (LVESVI) helps to predict postoperative left ventricular function in patients with ischemic cardiomyopathy. METHODS: We retrospectively assessed the ability of preoperative variables to predict death and the development of postoperative congestive heart failure in 41 patients with a preoperative ejection fraction of less than 0.30. RESULTS: A preoperative LVESVI of greater than 100 mL/m2 was identified as an independent predictor of death by Cox's proportional hazards model. Diabetes and a preoperative LVESVI of greater than 100 mL/m2 were independent predictive risk factors for the development of postoperative congestive heart failure. Postoperative congestive heart failure developed in 2 of the 23 patients (8.7%) who had a preoperative LVESVI of less than 100 mL/m2 and in 10 of the 16 patients (62.5%) who had a preoperative LVESVI of greater than 100 mL/m2. The actuarial survival rate during follow-up in patients who had a preoperative LVESVI of less than 100 mL/m2 was significantly greater than that in patients who had a preoperative LVESVI of greater than 100 mL/m2. The actuarial rate of freedom from congestive heart failure during the follow-up period also was greater in patients who had a preoperative LVESVI of less than 100 mL/m2. CONCLUSIONS: Our results suggest that the preoperative LVESVI predicts the development of postoperative congestive heart failure and the actuarial survival rate in patients with ischemic cardiomyopathy.

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Cite This Study

Yamaguchi et al. (1998) conducted a cohort in Ischemic cardiomyopathy (n=41). Preoperative LVESVI > 100 mL/m2 vs. Preoperative LVESVI < 100 mL/m2 was evaluated on Development of postoperative congestive heart failure. A preoperative LVESVI >100 mL/m2 was an independent predictor of death and associated with a higher rate of postoperative congestive heart failure compared to LVESVI <100 mL/m2 (62.5% vs 8.7%).

synapsesocial.com/papers/6aa4ae0dd2779b1afb94e392https://doi.org/10.1016/s0003-4975(97)01155-7
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