Iron and Vitamin B12 Deficiency Following Subtotal Gastrectomy

Case Studies1 July 1962Iron and Vitamin B12 Deficiency Following Subtotal GastrectomyReport of a Patient Developing Polycythemia Vera Following TreatmentFREDERICK A. KLIPSTEIN, M.D.FREDERICK A. KLIPSTEIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-57-1-133 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe development of polycythemia vera following treatment of megaloblastic anemia is rare and has been reported in only a few cases (1, 2). In all the reported cases the cause of the megaloblastic anemia was considered to be Addisonian pernicious anemia, for the patients were achlorhydric, they responded to treatment with vitamin B12or liver extract, and they showed no obvious signs of any of the other conditions which may be associated with megaloblastic anemia. Although such evidence does not establish the diagnosis of Addisonian pernicious anemia beyond all doubt, it is strongly suggestive. However, polycythemia vera following treatment of...References1. HINZ CF: Fatal polycythemia following pernicious anemia treated with vitamin B12. Ann. Intern. Med. 47: 544, 1957. LinkGoogle Scholar2. CHALMERSRICHARDS JNW: Megaloblastic anaemia alternating with polycythemia vera. Brit. Med. J. 1: 540, 1961. CrossrefMedlineGoogle Scholar3. HUNTNERROSS SHGI: A sugar containing medium for B12 assay with Euglena; application to body fluids. J. Protozool. 3: 101, 1956. CrossrefGoogle Scholar4. BAKERHERBERTFRANKPASHERHUNTNERWASSERMANSOBOTKA HVOISHLRH: A microbiological method for detecting folic acid deficiency in man. Clin. Chem. 5: 275, 1959. CrossrefMedlineGoogle Scholar5. SILVERMANGARDNERCONDIT MRCPT: A method for the detection of N-forminino-glutamic acid in the urine. J. Nat. Cancer Inst. 20: 71, 1958. MedlineGoogle Scholar6. 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Author, Article, and Disclosure InformationAffiliations: London,From the Department of Haematology of The Postgraduate Medical School of London and The Hammersmith Hospital, London, England.Dr. Klipstein is a Public Health Service trainee of the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health.Requests for reprints should be addressed to Frederick A. Klipstein, M.D., Department of Medicine, Francis Delafield Hospital, New York 32, New York. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByOsteomalacia following vagotomy and pyloroplastyPolycythaemia Masked by Megaloblastic AnæmiaPostgastrectomy malnutrition.Carcinogenic Hazards from Arsenic and Metal Containing DrugsPostgastrectomy blind loop syndromePeroral Biopsy of the Small IntestineFolate Deficiency in Polycythaemia Rubra VeraNeurologic Manifestations of Addisonian and Acquired Pernicious AnemiaCALCIUM METABOLISM AND THE BONES AFTER PARTIAL GASTRECTOMYCALCIUM METABOLISM AND THE BONES AFTER PARTIAL GASTRECTOMY 1 July 1962Volume 57, Issue 1Page: 133-140KeywordsMedical servicesMegaloblastic anemiaMetabolic disordersPathogenesisPernicious anemiaPolycythemiaPolycythemia veraSodiumThrombocytosisVitamin B12 deficiency Issue Published: 1 July 1962 PDF DownloadLoading ...