Key result
Protein cages and graphite/FeCo nanocrystals enable 7 T MRI macrophage imaging in mouse carotid atherosclerosis.
Novel nanoparticle platforms, including human protein cages and graphite/FeCo core-shell nanocrystals, offer multi-functional capabilities for 7 T MRI cellular imaging of macrophages in atherosclerotic plaques.
May advance 7 T cellular imaging of atherosclerosis; leaves open translation from murine models to clinical use.
Macrophages are important imaging targets for identifying and monitoring high-risk atherosclerotic plaque. Human protein cages and graphite/FeCo core-shell nanocrystals are unique, multi-functional nanoparticle platforms for cellular imaging.
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Kosuge et al. (2009) studied this question. Human protein cages and graphite/FeCo core-shell nanocrystals serve as novel nanoparticle platforms for 7 T MRI cellular imaging of macrophages in mouse carotid atherosclerosis.
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