Key result
Bilateral adrenalectomy and total thyroidectomy resolve hypercorticism and papillary microcarcinoma in a Carney Complex patient.
Case Report (n=1)
This case report highlights the importance of considering Carney complex in patients presenting with primary pigmented nodular adrenal disease and Cushing's syndrome.
Case report of CNC with Cushing's, IGT and psychiatric features should not change practice; leaves open need for larger series to define associations.
Carney complex (CNC) is a rare multisystem disorder, inherited in an autosomal dominant manner and characterized by distinctive spotty skin pigmentation, myxomas and endocrine abnormalities.We report a case of a 35-year-old patient diagnosed with Cushing's syndrome complicated with an impaired glucose tolerance (IGT) and a severe psychiatric disturbance.The diagnosis of CNC was made by having two major criteria, namely a primary pigmented nodular adrenal disease (PPNAD) and thyroid carcinoma.
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Hamza Elfekih (2017) conducted a case report in Cushing's syndrome and Carney Complex (n=1). Bilateral adrenalectomy and total thyroidectomy was evaluated on Clinical regression of hypercorticism signs and remission of tumors. Bilateral adrenalectomy and subsequent total thyroidectomy led to the clinical regression of hypercorticism signs, disappearance of impaired glucose tolerance, and complete remission of papillary microcarcinoma in a patient with Carney Complex.
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