Key result
Early postoperative silent ischemia is linked to a ~5-fold higher rate of clinical ischemic events.
Why the study?
Does early postoperative silent myocardial ischemia predict postoperative clinical ischemic events in patients with stable coronary disease undergoing peripheral vascular surgery?
Cohort (n=24)
Does early postoperative silent myocardial ischemia predict postoperative clinical ischemic events in patients with stable coronary disease undergoing peripheral vascular surgery?
Early postoperative silent myocardial ischemia is common after peripheral vascular surgery and is significantly associated with an increased risk of postoperative clinical ischemic events.
Answers are grounded in this paper and cite their sources.
Early postoperative silent ischemia may flag higher event risk after vascular surgery; hypothesis-generating and requires prospective trials before guiding practice.
Coronary disease causes the majority of perioperative complications after peripheral vascular surgery. Twenty-four patients with stable coronary disease undergoing peripheral revascularization were studied using continuous electrocardiographic monitoring to determine the incidence of perioperative asymptomatic myocardial ischemia and its relation to postoperative clinical ischemic events. Patients were monitored preoperatively (17 +/- 1 hours), intraoperatively and postoperatively (29 +/- 2 hours) using 4-channel calibrated amplitude-modulated units. Fifteen patients (63%) had early postoperative silent ischemia; 3 also had preoperative silent ischemia and 5 intraoperative transient ischemia. Patients with and without silent ischemia had similar clinical characteristics, perioperative antianginal medications and postoperative episodes of hemodynamic instability. However, 8 of 15 patients (53%) with silent ischemia had postoperative clinical ischemic events (2 had myocardial infarction, 2 had new congestive heart failure and 4 had new rest angina), versus only 1 of 9 patients (11%) without silent ischemia who had angina (p less than 0.05). Early postoperative silent myocardial ischemia occurs frequently after vascular surgery and is associated with postoperative clinical ischemic events.
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Ouyang et al. (1989) conducted a cohort in Stable coronary disease undergoing peripheral revascularization (n=24). Early postoperative silent myocardial ischemia vs. No early postoperative silent myocardial ischemia was evaluated on Postoperative clinical ischemic events (p=<0.05). Early postoperative silent myocardial ischemia was associated with a higher rate of postoperative clinical ischemic events compared to patients without silent ischemia.
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