Key result
Higher BaPWV and radial AI correlate positively with each other and increased carotid IMT.
Cross-Sectional (n=1,236)
In a Chinese population from Inner Mongolia, markers of arterial stiffness and atherosclerosis (BaPWV, radial AI, and carotid-IMT) are positively correlated with each other and with age.
Associations among arterial stiffness and atherosclerosis markers in Chinese adults are hypothesis-generating; prospective validation required before clinical adoption.
BACKGROUND: To investigate the relationship between brachial ankle pulse wave velocity (BaPWV), radial augmentation index (radial AI), ankle-brachial index (ABI), and carotid intima-media thickness (carotid-IMT), and to study the prevalence and characteristics of atherosclerosis and peripheral arterial disease in a Chinese population of Inner Mongolia. PATIENTS AND METHODS: Participants were recruited from Inner Mongolia in China through cluster multistage and random sampling. BaPWV, radial AI, ABI, and carotid-IMT values were measured in each subject. RESULTS: A total of 1,236 participants from natural population of Inner Mongolia in China were included in this study. The average ABI value was 1.082 ± 0.093. The average values of common carotid, internal carotid, and carotid artery bifurcation IMT were 0.70 ± 0.21, 0.77 ± 0.24, and 0.78 ± 0.25 mm, respectively. The average value of BaPWV was 1450.5 ± 301.5 cm/s. The average value of radial AI was 78.9 ± 16.8 %. BaPWV, radial AI, and carotid-IMT values were positively correlated with ages significantly. BaPWV values were positively correlated with radial AI significantly. BaPWV values were positively correlated with values of common carotid, internal carotid, and carotid artery bifurcation IMT respectively. Radial AI values were positively correlated with the values of common carotid, internal carotid, and carotid artery bifurcation IMT respectively. A U-shaped relationship was observed that radial AI values were decreased at first and then increased as ABI values increased. CONCLUSIONS: The data suggests that BaPWV, radial AI, and carotid-IMT values are positively correlated with each other, and AI values are correlated with ABI values in a U-shaped curve in a Chinese population of Inner Mongolia.
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Wang et al. (2011) conducted a cross-sectional in Atherosclerosis and peripheral arterial disease (n=1,236). Vascular markers (BaPWV, radial AI, ABI, carotid-IMT) was evaluated on Relationship between BaPWV, radial AI, ABI, and carotid-IMT. Vascular markers including BaPWV (mean 1450.5 cm/s) and radial AI (mean 78.9%) were positively correlated with each other and with carotid intima-media thickness in a Chinese population.
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