Key result
ECG LVH criteria poorly reflect true hypertrophy but flag early systolic dysfunction like GLPS below -13%.
Why the study?
Do ECG criteria of LVH reflect early systolic LV dysfunction measured by tissue Doppler and LV strain in patients with aortic stenosis and preserved LVEF?
Cross-Sectional (n=80)
Do ECG criteria of LVH reflect early systolic LV dysfunction measured by tissue Doppler and LV strain in patients with aortic stenosis and preserved LVEF?
p-value: p=<0.05
ECG criteria for LVH, specifically the Cornell index and product, can serve as markers for early systolic LV dysfunction (reduced GLPS) in patients with aortic stenosis and preserved ejection fraction.
ECG criteria may flag early systolic dysfunction in AS with preserved EF; hypothesis-generating and needs prospective validation before guiding care.
AIM: to study relation between electrocardiographic (ECG) criteria of left ventricular hypertrophy (LVH) and parameters of tissue Doppler (TD) and LV strain in patients with aortic stenosis (AS) with preserved LV ejection fraction. MATERIAL AND METHODS: We examined 80 patients with degenerative AS of all degrees of severity. Examination included history, blood serum cholesterol and creatinine, 12 lead ECG, routine echocardiography (EchoCG), TD, and LV global longitudinal peak strain (GLPS) in apical positions of 2-dimensional EchoCG. RESULTS: ECG criteria demonstrated low sensitivity relative to presence of real LVH. Average values of TD and (GLPS) were lowered in patients with AS. Correlation analysis revealed reverse relationship between TD and GLPX (<0.05). ROC-curve analysis showed very good quality of informativeness of the Cornell index and product for diagnosis of GLPX lowering below - 13%. CONCLUSION: ECG criteria of LVH poorly reflect real LVH but are markers of early systolic LV dysfunction.
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Чумакова et al. (2015) conducted a cross-sectional in Aortic stenosis with preserved LV ejection fraction (n=80). Electrocardiographic criteria of left ventricular hypertrophy was evaluated on Relation between ECG criteria of LVH and parameters of tissue Doppler and LV strain (p=<0.05). Electrocardiographic criteria of left ventricular hypertrophy poorly reflect true hypertrophy but are informative for diagnosing early systolic dysfunction, such as GLPS lowering below -13%.
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