Key result
CHF presentation in LV aneurysm surgery is linked to ~11-fold higher early mortality than angina.
Why the study?
What are the early and late outcomes of surgical treatment for post-infarction left ventricular aneurysms, and how do they vary by preoperative indication?
Cohort (n=119)
What are the early and late outcomes of surgical treatment for post-infarction left ventricular aneurysms, and how do they vary by preoperative indication?
Absolute Event Rate: 14.7% vs 1.3%
p-value: p=<0.01
Surgical treatment of post-infarction left ventricular aneurysms is associated with significantly better early and late survival in patients presenting with angina or arrhythmias compared to those presenting with congestive heart failure.
Heart failure presentation warrants perioperative caution in LV aneurysm repair; this Level 3 cohort leaves open optimal indication-based selection.
The early and late results of a 4 year surgical experience with 119 left ventricular aneurysms (LVA) are analyzed. The most common indication for surgery was angina in 78 patients, congestive heart failure (CHF) in 34, arrhythmia in 5 and recurrent embolism in 1. One patient was operated on prophylactically. There were 112 "anterior" and 7 "posterior" aneurysms. Preoperative ventricular function was significantly worse in the CHF group. LVA resection was carried out in 105 patients and a plicature in other 14. In 92 cases the procedure was combined with a myocardial revascularization. Additional cardiac procedures were performed in 14 patients. Overall early (5.9%) and late mortality (18.7%) was significantly higher in the CHF group than in the angina group (14.7% versus 1.3%, p less than 0.01, and 37.9% versus 12.9%, p less than 0.01, respectively). Associated surgical procedures (p less than 0.001) and acuity of the LVA (p less than 0.05) also increased the operative risk. The 5 year-survival was better for the angina group (85.7 +/- 4%) and arrhythmias group (80 +/- 22%) than for CHF patients (46.7 +/- 19%) (p = 0.052). Functional improvement was uniform between survivors of all groups (73.2%). In 15 patients with pre- and postoperative studies hemodynamic parameters were found improved although only a global contractile score did reach significant levels (p less than 0.005).(ABSTRACT TRUNCATED AT 250 WORDS)
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González‐Santos et al. (1985) conducted a cohort in Post-infarction left ventricular aneurysm (n=119). Congestive heart failure presentation vs. Angina presentation was evaluated on Early mortality (p=<0.01). In surgical treatment for post-infarction left ventricular aneurysms, presentation with congestive heart failure had higher early mortality than angina (14.7% vs 1.3%, p<0.01).
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