Key result
Radial artery grafts during OPCAB are linked to increased symptom recurrence and adverse cardiac events.
Why the study?
Does radial artery graft use improve outcomes in patients undergoing off-pump coronary artery bypass?
Cohort (n=591)
Does radial artery graft use improve outcomes in patients undergoing off-pump coronary artery bypass?
In patients undergoing off-pump coronary artery bypass, the use of radial artery grafts was associated with an increased risk of symptom recurrence and adverse cardiac events.
Radial artery grafts may increase risks in off-pump CABG; leaves open need for RCTs to guide conduit selection.
Radial artery is commonly used as a conduit for surgical revascularization. There is scarce data on the effect of radial artery use on outcome following off-pump coronary artery bypass. We prospectively evaluated 591 patients undergoing off-pump coronary artery bypass. Radial artery grafts were used in 398 of these patients (mean age, 67.6 +/- 10.4 years; mean follow-up, 37.7 +/- 13.4 months). Symptom recurrence (angina, congestive heart failure), adverse cardiac events (myocardial infarction, coronary re-intervention, sudden cardiac death), and overall mortality were recorded. Multivariate Cox regression analysis was used to evaluate predictors of endpoints. Patients with and without radial artery grafts were similar with respect to preoperative risk factors. Recurrent angina developed in 29 patients, congestive heart failure in 5, and myocardial infarction in 9. Coronary arteriography was performed in 27 patients, and 23 underwent re-intervention. Radial artery graft was an independent predictor of increased symptom recurrence and adverse cardiac events. Patients with radial artery grafts also had a tendency towards more angina recurrence, coronary re-intervention, and sudden cardiac death.
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Gürbüz et al. (2007) conducted a cohort in Off-pump coronary artery bypass (n=591). Radial artery graft vs. No radial artery graft was evaluated on Symptom recurrence, adverse cardiac events, and overall mortality. Radial artery graft use during off-pump coronary artery bypass was an independent predictor of increased symptom recurrence and adverse cardiac events.
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