Key result
Anemia in HF is linked to ~5-fold greater mortality, while iron sulfate improves LVEF.
Why the study?
Does iron sulfate improve ejection fraction and functional capacity in patients with chronic heart failure and iron deficiency anemia?
Population
Patients with Chronic Heart Failure (CHF)
Comparison
Iron sulfate added to standard heart failure… vs Patients with normal hemoglobin levels and…
Design
Cohort
Authors
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Anemia may signal higher mortality risk in chronic HF; leaves open whether iron repletion improves outcomes.
Cohort
Does iron sulfate improve ejection fraction and functional capacity in patients with chronic heart failure and iron deficiency anemia?
Relative Risk: 4.9
Treating iron deficiency anemia with iron sulfate in patients with chronic heart failure is associated with improved ejection fraction and quality of life.
Rafie et al. (2012) conducted a cohort in Chronic Heart Failure. Anemia and iron sulfate treatment vs. Normal hemoglobin levels was evaluated on Mortality and ejection fraction (4.9 times higher mortality). Anemia in chronic heart failure was associated with a 4.9 times higher mortality rate compared to normal hemoglobin, while iron sulfate treatment for iron deficiency improved ejection fraction.
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