Key result
Acoustic radiation force impulse imaging distinguishes diabetic nephropathy stages from healthy controls with ~84% sensitivity.
Why the study?
Can acoustic radiation force impulse imaging evaluate changes in renal parenchyma elasticity in patients with diabetic nephropathy compared to healthy controls?
Observational (n=395)
Can acoustic radiation force impulse imaging evaluate changes in renal parenchyma elasticity in patients with diabetic nephropathy compared to healthy controls?
Acoustic radiation force impulse imaging can detect changes in renal elasticity associated with diabetic nephropathy and distinguish between most disease stages.
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May support noninvasive diabetic nephropathy staging; leaves open need for prospective validation before clinical use.
Göya et al. (2015) conducted an observational in Diabetic nephropathy (n=395). Acoustic radiation force impulse imaging vs. Healthy control subjects was evaluated on Shear-wave velocity. Acoustic radiation force impulse imaging distinguished diabetic nephropathy stages from healthy controls, with a threshold of 2.43 m/s yielding 84.1% sensitivity and 67.3% specificity.