Key result
Male gender and higher BMI associate with ~6ms longer QRS durations, explained by larger heart size.
Why the study?
The relative impact of concurrent changes in heart size and conduction velocity on QRS duration across demographics is poorly understood.
Cross-Sectional (n=400)
Absolute Event Rate: 90% vs 84%
p-value: p=<0.001
Differences in QRS duration across gender and BMI groups are primarily driven by variations in heart size rather than conduction velocity.
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Sex- and BMI-related QRS differences should not alter device thresholds; leaves open whether heart size indexing refines conduction assessment.
Qian et al. (2023) conducted a cross-sectional in Without self-reported cardiovascular diseases (n=400). Male gender and higher BMI vs. Female gender and healthy weight was evaluated on QRS duration (ms) (p=<0.001). Male gender and higher BMI were associated with longer QRS durations (90ms in males vs 84ms in females, P<0.001), primarily explained by larger heart size rather than conduction velocity.
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