Key result
Assisted peritoneal dialysis shows equivalent two-year quality of life and physical function versus in-center hemodialysis.
Why the study?
In-center hemodialysis is associated with functional decline in older patients, and longitudinal comparisons of quality of life between assisted peritoneal dialysis and in-center hemodialysis were needed.
Does assisted peritoneal dialysis improve quality of life and physical function compared to in-center hemodialysis in frail older patients with end-stage kidney disease?
Population
106 aPD patients matched with 100 HD patients from 20 renal centers
Comparison
Assisted peritoneal dialysis vs in-center hemodialysis
Design
Multicenter matched longitudinal study
Follow-up
2 years
Authors
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Supports aPD as home option with QoL equivalent to in-center HD in frail elderly; leaves open causal confirmation pending randomized trials.
Cohort (n=206)
Yes
Does assisted peritoneal dialysis improve quality of life and physical function compared to in-center hemodialysis in frail older patients with end-stage kidney disease?
Assisted peritoneal dialysis provides equivalent quality of life and physical function outcomes to in-center hemodialysis for frail older patients with end-stage kidney disease, offering a valid home-based alternative.
Iyasere et al. (2019) conducted a cohort in End-stage kidney disease (n=206). Assisted peritoneal dialysis vs. In-center hemodialysis was evaluated on Longitudinal changes in quality of life and physical function. Assisted peritoneal dialysis yielded equivalent longitudinal quality of life and physical function outcomes compared to in-center hemodialysis over 2 years, with a 60.6% overall dropout rate.
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