Key result
Combined high BMI and high neck circumference linked to ~42% greater incident hypertension risk.
Why the study?
The study aimed to investigate the association between BMI combined with neck circumference and the risk of hypertension.
Does the combination of high BMI and high neck circumference increase the risk of hypertension in normotensive individuals?
Cohort (n=43,600)
Yes
Does the combination of high BMI and high neck circumference increase the risk of hypertension in normotensive individuals?
Hazard Ratio: 1.422 (95% CI 1.337–1.512)
Absolute Event Rate: 123.84% vs 71.82%
p-value: p=<0.001
Combining BMI and neck circumference improves the prediction of incident hypertension risk compared to either measure alone.
Combined BMI-neck circumference may refine hypertension risk stratification; extends anthropometric data but leaves open prospective validation.
Objective: This study aimed to investigate the association between BMI combined with neck circumference and the risk of hypertension. Methods: We selected participants from the Kailuan study in 2014 who were normotensive as our research subjects. We compared the risk of hypertension among individuals in group 1 (non-obese with low neck circumference), group 2 (non-obese with high neck circumference), group 3 (obese with low neck circumference), and group 4 (obese with high neck circumference). Results: After a median observation period of 3.86 years, hypertension occurred in 13,383 participants. Subjects in Group 2, 3, and 4 had significantly higher risks of hypertension compared to Group 1, with hazard ratios (HRs) of 1.066 (95% CI: 1.025, 1.110), 1.322 (95% CI: 1.235, 1.415), and 1.422 (95% CI: 1.337, 1.512), respectively. Additionally, adding BMI to a conventional model had a greater incremental effect on predicting hypertension compared to adding neck circumference alone. However, considering both BMI and neck circumference together further improved the prediction of hypertension. Conclusion: Individuals with both high BMI and high neck circumference face a higher risk of hypertension. Moreover, BMI is a superior predictor of hypertension risk compared to neck circumference, but using both of these measures can further enhance the accuracy of hypertension risk prediction.
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Ren et al. (2023) conducted a cohort in Hypertension (n=43,600). High BMI and high neck circumference vs. Low BMI and low neck circumference was evaluated on Incidence of hypertension (HR 1.422, 95% CI 1.337-1.512, p=<0.001). Individuals with both high BMI and high neck circumference had a significantly higher risk of developing hypertension compared to those with low BMI and low neck circumference (HR 1.422).
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