Key result
RF ablation of cardiac parasympathetic ganglia shows potential for refractory pediatric neurally mediated syncope.
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Not ready for routine use in refractory pediatric syncope; hypothesis-generating and requires prospective trials.
Syncope is a common presenting complaint in pediatric cardiology outpatient referrals. While some causes of syncope such as ventricular tachyarrhythmias or bradyarrhythmias are inherently cardiac in nature, neutrally mediated syncope (NMS) can also occur owing to an imbalance of sympathetic and parasympathetic tone. Enhanced parasympathetic tone via the vagus nerve can cause slowing of the sinus or atrioventricular (AV) nodes, resulting in sinus pauses or AV block, respectively.1 At times, these patients will require pacemaker implantation if medical treatment fails.
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Kumthekar et al. (2020) conducted a review in Neutrally mediated syncope (NMS). Radiofrequency ablation of cardiac parasympathetic ganglia was evaluated. Radiofrequency ablation of cardiac parasympathetic ganglia is discussed as a potential treatment for pediatric patients with neutrally mediated syncope who fail medical therapy.
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