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December 19, 2008Journal of Cardiovascular Electrophysiology

Selective Vagal Denervation of the Sinus and Atrioventricular Nodes, Guided by Vagal Reflexes Induced by High Frequency Stimulation, to Treat Refractory Neurally Mediated Syncope

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Key result

Selective vagal denervation guided by high frequency stimulation provided 9 months of symptom relief in a patient with refractory vasovagal syncope, followed by recurrence of vagal activity.

Why the study?

Does selective vagal denervation guided by high frequency stimulation prevent syncope in a patient with refractory neurally mediated syncope?

Population

1 15-year-old female patient with frequent episodes of vasovagal syncope refractory to non-pharmacological…

Design

Case_report

Follow-up

11 months

Authors

MSMaurício ScanavaccaElectrophysiologyDHDenise HachulHospital das Clínicas da Faculdade de Medicina da Universidade de São PauloCPCristiano PisaniElectrophysiology

Discussion

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Implication

May provide temporary relief in refractory vasovagal syncope; leaves open durability of selective vagal denervation.

Study Design

Type

Case Report (n=1)

Structured PICO

Does selective vagal denervation guided by high frequency stimulation prevent syncope in a patient with refractory neurally mediated syncope?

P
Population
1 15-year-old female patient with frequent episodes of vasovagal syncope refractory to non-pharmacological and pharmacological measures.
I
Intervention
Selective vagal denervation of the sinus and atrioventricular nodes, guided by high frequency stimulation (HFS), using radiofrequency pulses on the left and right sides of the interatrial septum.
O
Outcome
Recurrence of neurally mediated syncope and tilt-table test responsepatient reported

Selective vagal denervation guided by high frequency stimulation may provide temporary relief for refractory vasovagal syncope, but vagal reinnervation and symptom recurrence can occur within a year.

Cite This Study

Scanavacca et al. (2008) conducted a case report in Refractory neurally mediated syncope (n=1). Selective vagal denervation guided by high frequency stimulation was evaluated on Clinical symptoms and vagal responses. Selective vagal denervation guided by high frequency stimulation provided 9 months of symptom relief in a patient with refractory vasovagal syncope, followed by recurrence of vagal activity.

synapsesocial.com/papers/6a15b80b814bf8ec9a4ef71ehttps://doi.org/10.1111/j.1540-8167.2008.01385.x
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Also Consider

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