Key result
Selective RF catheter ablation of atrial sites with evoked vagal reflexes resulted in 2 of 7 patients remaining asymptomatic without antiarrhythmic medication at a mean follow-up of 8.3 months.
Why the study?
Does selective atrial vagal denervation guided by evoked vagal reflex prevent recurrences in patients with vagal-induced paroxysmal atrial fibrillation?
Population
10 patients with episodes suggestive of vagal-induced paroxysmal atrial fibrillation and no structural heart…
Comparison
Selective radiofrequency catheter ablation of… vs Circumferential pulmonary vein ablation.
Design
Case_series
Follow-up
mean 8.3 +/- 2.8 months
Authors
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Limited efficacy in this case series cautions against clinical use; leaves open benefit in controlled trials for vagal paroxysmal AF.
Observational (n=10)
Does selective atrial vagal denervation guided by evoked vagal reflex prevent recurrences in patients with vagal-induced paroxysmal atrial fibrillation?
Absolute Event Rate: 28.6% vs 100%
Selective atrial vagal denervation guided by evoked vagal reflexes showed limited efficacy, with only a minority of patients remaining free of AF recurrences without antiarrhythmic drugs.
Scanavacca et al. (2006) conducted an observational in Paroxysmal Atrial Fibrillation (n=10). Selective radiofrequency catheter ablation of atrial sites with evoked vagal reflexes vs. Circumferential pulmonary vein ablation (in patients without evoked vagal reflexes) was evaluated on Prevention of AF recurrences (remaining asymptomatic without antiarrhythmic medication). Selective RF catheter ablation of atrial sites with evoked vagal reflexes resulted in 2 of 7 patients remaining asymptomatic without antiarrhythmic medication at a mean follow-up of 8.3 months.
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