Key result
Increased perceived stress links to higher CRP levels from adolescence to young adulthood.
Why the study?
Little is understood about how systemic inflammation changes over time in young individuals and how psychosocial stress may influence these inflammatory changes earlier in the lifespan.
Does psychosocial stress influence changes in C-reactive protein (CRP) from mid-adolescence to young adulthood?
Population
350 individuals recruited during mid-adolescence
Comparison
Between- and within-person differences in perceived stress, major life events, and daily interpersonal stress
Design
Three-wave longitudinal study
Follow-up
4-year period
Authors
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Stress-CRP link in youth is hypothesis-generating; leaves open causality and precludes practice change without trials.
Cohort (n=350)
Does psychosocial stress influence changes in C-reactive protein (CRP) from mid-adolescence to young adulthood?
Contemporaneous experiences of perceived stress are associated with higher systemic inflammation (CRP) during the transition from adolescence to young adulthood.
Chiang et al. (2019) conducted a cohort in Systemic inflammation (n=350). Psychosocial stress (perceived stress, life events, daily stress) vs. Lower stress levels was evaluated on C-reactive protein (CRP) trajectory. Within-person increases in perceived stress were associated with higher C-reactive protein levels over a 4-year period from mid-adolescence to young adulthood.
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