Ion-Exchange Route to Au–CuxOS Yolk–Shell Nanostructures with Porous Shells and Their Ultrasensitive H2O2 Detection

In this letter, Au-Cu(x)OS yolk-shell nanostructures with porous shell are prepared through a facile ion exchange route from Au@Cu(2)O core-shell nanostructures. The as-prepared yolk-shell nanostructures exhibit ultrasensitive enzyme-free detection of H(2)O(2) molecules with higher sensitivity (50.41 μA μM(-1)) and lower detection limit (0.01 μM) as well with excellent anti-interference capacity in comparison with both hollow Cu(x)OS nanospheres and Au nanoparticles. Therefore, the obtained Au-Cu(x)OS yolk-shell nanostructures have potential application in ultralow concentration enzyme-free H(2)O(2) detection for biomedicine diagnosis.