Key result
Chronic inflammation requires large prospective studies to clarify its causal role in CHD pathogenesis.
Key points are not available for this paper at this time.
Should not alter CHD management; leaves infection-mediated inflammation's causal role open for prospective confirmation.
There is growing interest in the role of chronic inflammation -- possibly mediated by infection -- in the pathogenesis of coronary heart disease (CHD). Because most studies have been cross-sectional, it has been difficult to draw conclusions about cause and effect. In this large prospective study, researchers tried to clarify this relationship. The …
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KI Marton (2000) studied this question. Chronic inflammation, possibly mediated by infection, requires large prospective studies to clarify its causal role in the pathogenesis of coronary heart disease.
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