Why the study?
Perioperative pain management influences outcomes and mortality after surgery in elderly patients with proximal femur fractures, but comparative data on anesthesia techniques were needed.
Does prolonged compartment psoas block improve pain control and safety outcomes compared to spinal and general anesthesia in elderly patients with proximal femur fractures?
RCT (n=150)
1:1:1:1:1
No
Does prolonged compartment psoas block improve pain control and safety outcomes compared to spinal and general anesthesia in elderly patients with proximal femur fractures?
Absolute Event Rate: 0% vs 20%
p-value: p=<0.001
Prolonged compartment psoas block provides superior pain control and reduces myocardial injury and opioid side effects compared to spinal and general anesthesia in elderly patients with proximal femur fractures.
Supports early prolonged psoas compartment block in elderly hip fracture patients; extends RCT evidence for regional anesthesia reducing myocardial injury.
Proximal femur fractures are most common fractures in the elderly and associated with significant mortality and morbidity, with high economic and social impact. Perioperative pain management influence outcomes and mortality after surgery with early mobilization being possible. The goal of the study was to compare the efficacy and safety of the compartment psoas block with spinal and general anesthesia. We included 150 patients in this randomized controlled study. The most effective technique of analgesia was prolonged compartment psoas block, which starts from hospital admission and 3 days after surgery, and was associated with better pain control, decreased opioid consumption, better sleep quality, earlier mobilization after surgery, decreased incidence of opioidassociated vomiting/nausea and myocardial injury. There were no difference in the incidence of hospital acquired pneumonia and delirium.
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Кучин et al. (2020) conducted an RCT in Proximal femur fracture (n=150). Prolonged psoas compartment block vs. General anesthesia or spinal anesthesia with systemic analgesia was evaluated on Nalbuphine consumption in the first 24 hours (mg) (p=<0.001).
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