Key result
Bevacizumab and radiotherapy yield biopsy-proven remission without surgery in a case of extensive scalp angiosarcoma.
Why the study?
Does bevacizumab and radiotherapy induce remission in patients with extensive scalp angiosarcoma who are not surgical candidates?
Case Report (n=1)
Does bevacizumab and radiotherapy induce remission in patients with extensive scalp angiosarcoma who are not surgical candidates?
Bevacizumab combined with radiotherapy may offer a non-surgical treatment option for extensive scalp angiosarcoma, achieving biopsy-proven remission in an elderly patient.
May offer non-surgical remission option for inoperable scalp angiosarcoma in elderly patients; single case leaves open need for prospective validation.
Angiosarcoma (AS) is a rare and aggressive vascular neoplasm with very poor prognosis. Patients with extensive cutaneous AS who are not surgical candidates have very limited options since there is no standard treatment. Treatment options include radiation, chemotherapy, and angiogenesis inhibitor with varying success rates. Here, we report a case an 88 year old patient with extensive scalp angiosarcoma having biopsy proven remission with bevacizumab and radiotherapy without undergoing surgery.
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Yao et al. (2011) conducted a case report in Extensive scalp angiosarcoma (n=1). Bevacizumab and radiotherapy was evaluated on Biopsy proven remission. Bevacizumab and radiotherapy led to biopsy-proven remission in an 88-year-old patient with extensive scalp angiosarcoma without undergoing surgery.
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