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September 1, 1969CirculationOpen Access

Factors Related to ST-Segment Depression after Exercise in Middle-Aged Chinese Men

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Key result

Hypertension is linked to a ~4-fold increase in post-exercise ST-segment depression versus normotensive controls.

  • n=1,346

Population

1,346 healthy middle-aged Chinese men

Design

Cross-sectional

Authors

BCBENJAMIN N. CHAINGUniversity of WashingtonEAE. Russell AlexanderGhana College of Physicians and SurgeonsRBRobert A. BruceUniversity of Iowa

Discussion

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Implication

May not signal ischemia in hypertensive men; leaves open non-atherosclerotic mechanisms for prospective validation.

Study Design

Type

Cross-Sectional (n=1,346)

Structured PICO

P
Population
1,346 healthy middle-aged Chinese men who underwent a graded treadmill test of maximal exercise.
E
Exposure
Graded treadmill test of maximal exercise
O
Outcome
Post-exercise ST-segment depressionsurrogate

In middle-aged Chinese men, post-exercise ST-segment depression is strongly associated with higher systemic blood pressure and age, highlighting non-atherosclerotic causes of this ECG finding.

Cite This Study

CHAING et al. (1969) conducted a cross-sectional in Healthy (n=1,346). Hypertension vs. Age-matched normotensive controls was evaluated on Post-exercise ST-segment depression. Hypertension was associated with at least a fourfold increase in post-exercise ST-segment depression compared with age-matched normotensive controls in healthy middle-aged Chinese men.

synapsesocial.com/papers/6aa50d6668dd06f3d4aa299ehttps://doi.org/10.1161/01.cir.40.3.315

Topics

Hypertension management
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Blood Pressure and Hypertensive Disease Among Negroes and Whites1964 · 177 citations
  2. 2Myocardial Infarction After Normal Responses to Maximal Exercise1968 · 43 citations
  3. 3Overweight and Hypertension1969 · 577 citations