What is the clinical evidence from this study?

Study design: Cohort. Population: Percutaneous coronary intervention (n=662). Intervention: Newly detected diabetes vs. Other glycometabolic states. Primary outcome: Major cardiac events.

What does this research mean for the field?

Newly detected diabetes affects approximately 16% of patients undergoing percutaneous coronary intervention but is not an independent predictor of major cardiac events at 12 months. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 9, 2009European Heart Journal

Prevalence and outcome of newly detected diabetes in patients who undergo percutaneous coronary intervention

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Key result

Newly detected diabetes after PCI fails to independently predict 12-month major cardiac events.

n=662

Why the study?

Is newly detected diabetes an independent predictor of major cardiac events in patients undergoing PCI?

Population

662 consecutive patients referred for percutaneous coronary intervention between November 2005 and May 2006.

Comparison

Newly detected diabetes vs Patients with known diabetes, impaired glucose…

Design

Cohort

Follow-up

12 months

Authors

JHJesús M. de la HeraCentral University Hospital of Asturias EDElías DelgadoUniversidad de Oviedo EHEduany HernándezHospital Universitario de Canarias

Discussion

Member takes

Implication

High prevalence supports diabetes screening in PCI patients; leaves open its independent prognostic value beyond standard risk factors.

Study Design

Type

Cohort (n=662)

Multicenter

Structured PICO

Is newly detected diabetes an independent predictor of major cardiac events in patients undergoing PCI?

Population

662 consecutive patients referred for percutaneous coronary intervention, followed for 12 months to assess glycometabolic state and outcomes.

Exposure

Newly detected diabetes (assessed via oral glucose tolerance test at 15 days after hospital discharge)

Comparator

Patients with known diabetes, impaired glucose tolerance, impaired fasting glucose, or normal glucose regulation

Outcome

Major cardiac events after admission and during 12 months of follow-uphard clinical

Newly detected diabetes is highly prevalent (16.2%) in patients undergoing PCI but does not independently predict major cardiac events at 12 months.

Limitations

Requires independent confirmation in other series to draw general conclusions on the whole spectrum of percutaneous interventions

Cite This Study

Hera et al. (2009) conducted a cohort in Percutaneous coronary intervention (n=662). Newly detected diabetes vs. Other glycometabolic states was evaluated on Major cardiac events. Newly detected diabetes was present in 16.2% (95% CI 13.1-19.8) of patients undergoing PCI but was not an independent predictor of major cardiac events at 12 months.

synapsesocial.com/papers/6aa50f40814b48fd3caa2cb5 https://doi.org/10.1093/eurheartj/ehp278

Topics

Coronary artery disease

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Prevalence and outcome of newly detected diabetes in patients who undergo percutaneous coronary intervention

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Topics

Prevalence and outcome of newly detected diabetes in patients who undergo percutaneous coronary intervention

Discussion

Member takes

Implication

Study Design

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider