Key result
Losartan linked to angioedema in 13 reported cases, prompting caution in patients with prior episodes.
Why the study?
Is losartan associated with the development of angioedema?
Case Report (n=13)
Is losartan associated with the development of angioedema?
Losartan use is associated with the development of angioedema, suggesting that angiotensin II receptor blockers should be prescribed with caution in patients with a history of angioedema.
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May warrant vigilance with ARBs in prior angioedema; case reports leave risk magnitude and causality open for prospective study.
Rijnsoever et al. (1998) conducted a case report in Angioedema (n=13). Losartan was evaluated on Angioedema. Losartan use was associated with the onset of angioedema in 13 reported cases, suggesting angiotensin II antagonists should be used with caution in patients with a history of angioedema.
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