Key result
Zebrafish models streamline cardiovascular drug discovery via high-throughput chemical screening.
Why the study?
Despite scientific progress, approvals for cardiovascular drugs have stagnated significantly compared to other fields during past years.
Design
Review
Authors
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Zebrafish may accelerate preclinical cardiovascular screening; leaves open translation to human therapies pending validation.
Zebrafish represent a promising in vivo platform for high-throughput screening to streamline cardiovascular drug discovery.
Pott et al. (2019) conducted a review in Cardiovascular disease. Zebrafish models was evaluated. Zebrafish serve as an advantageous in vivo organism to model human cardiovascular diseases and a platform for high-throughput chemical compound screening to streamline drug discovery.
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